Dr. Mark D'onofrio, M.D.

Orthopedic Surgery
116 procedures 4 hospitals Lancaster, OH

Contact & Location

740-687-3346
Phone: 740-687-3346
Practice phone listed in the NPI registry
2656 N Columbus St Ste D
Lancaster, OH 43130
Current practice address per the CMS NPPES registry (self-reported to the registry, last updated June 2025). Registry checked August 2026.
NPI: 1316925811
Credentials: M.D.
Active Medicare provider (NPI verified)
20 years of practice experience
Licensed M.D.
Licensed surgical specialist
Board-certified orthopedic surgeon
Contact information available
Find Practice on Google Maps
National Comparison by Procedure
Hip 37 vs 36 national avg (4,542 surgeons)
Knee 62 vs 45 national avg (6,612 surgeons)
Shoulder 17 vs 29 national avg (2,217 surgeons)

Dr. D'onofrio performs more knee replacement procedures than 79% of orthopedic surgeons in Ohio, based on 2024 Medicare claims volume.Derived from the state ranking shown on this page: #64 of 305 ranked knee surgeons in Ohio.

About Dr. D'onofrio

Dr. Mark D'onofrio is a board-certified orthopedic surgeon practicing in Lancaster, Ohio. A Medicare provider since 2006, Dr. D'onofrio completed 62 knee replacements (#64 in Ohio), 37 hip replacements, and 17 shoulder replacements in the latest annual CMS data, totaling 116 Medicare-verified procedures.

In Ohio, Dr. D'onofrio performs above the state average in knee (62 vs 41), near the state average in hip (37 vs 32), below the state average in shoulder (17 vs 29).

Dr. D'onofrio performs all three major joint replacement procedures (hip, knee, and shoulder), indicating a broad scope of orthopedic practice. The largest share is knee replacements (62 cases), followed by hip replacements (37) and shoulder replacements (17).

Dr. D'onofrio is the only orthopedic surgeon in Lancaster represented in the current Medicare dataset, serving as the primary local option for patients considering joint replacement surgery in the area.

Dr. D'onofrio's Medicare record spans 12 years from 2013 through 2024. Procedure volume has remained consistent during that period, ranging from 112 to 193 procedures per year, reflecting a steady joint replacement practice.

Among 6,612 knee replacement surgeons tracked nationally, Dr. D'onofrio's 62 verified procedures is above the national average of 45.

Verified Medicare Cases

Knee Replacement
62 verified cases
#64 in Ohio
Hip Replacement
37 verified cases
#52 in Ohio
Shoulder Replacement
17 verified cases
#60 in Ohio
Estimated 2024 total: 380 – 480 procedures (all insurers)
Medicare fee-for-service share of national volume in 2024: 23% to 28% for knee replacement, 25% to 33% for hip replacement, 29% to 37% for shoulder replacement
How is this estimated?

Medicare Part B fee-for-service claims are one payer stream among several, and the share they represent differs by procedure. In 2024 it was 23% to 28% for knee replacement, 25% to 33% for hip replacement, 29% to 37% for shoulder replacement. Each verified count above is divided by its own procedure's range, and the results are added, to estimate total practice volume across all payers. The verified Medicare count is the definitive, audited figure; this is a range derived from published national volume projections, not a measurement, and an individual practice can sit well outside it: how these ranges are derived, and their sources.

How Dr. D'onofrio Compares

Procedure volume compared to the Ohio state average.

Hip Average
37 Avg: 32
Knee High
62 Avg: 41
Shoulder Below Avg
17 Avg: 29
Dr. D'onofrio Ohio Average

Volume Trend Analysis

Dr. D'onofrio's procedure volume has been consistent across 12 years of Medicare data, ranging from 112 to 193 procedures per year. This stability suggests a well-established joint replacement practice.

Years of Data 12
2024 Volume 116
Peak Volume 193 (2016)
Trend Stable

Hospital Affiliations & Quality

H
Fairfield Medical Center
2/5
Lancaster, OH
Similar to national avg
H
Hocking Valley Community Hospital
Logan, OH
Low case volume
H
Genesis Hospital
4/5
Zanesville, OH
Low case volume
H
Ohiohealth O'Bleness Hospital
4/5
Athens, OH
Low case volume

Quality ratings and complication rates are hospital-level metrics from CMS Hospital Compare and do not reflect individual surgeon performance. Star ratings updated quarterly. Complication data covers a rolling 3-year period.

Patient Resources: Preparing for Knee Replacement

If you are considering knee replacement surgery, these evidence-based guides can help you prepare and recover:

Knee Replacement Recovery Overview

Recovery timelines vary by patient, but here is a general overview of what to expect after knee replacement surgery:

Week 1-2 Walking with assistive device. Knee bending exercises begin immediately. Ice therapy and elevation for swelling control.
Week 3-6 Increased range of motion (target 90 degrees). Walking longer distances. Physical therapy intensifies with strengthening exercises.
Week 7-12 Most patients walk without assistive devices. Resume driving and desk work. Continue PT for strength and flexibility.
Month 4-6 Near-full recovery. Resume most recreational activities. Some swelling and stiffness may persist but continues improving.

Individual recovery varies based on overall health, age, and adherence to physical therapy. View full knee replacement recovery guide and product recommendations

Frequently Asked Questions About Dr. D'onofrio

How does Dr. D'onofrio's procedure volume compare to other Ohio surgeons?

Dr. D'onofrio has performed 116 Medicare-verified joint replacement procedures. This is significantly above the Ohio average of 59 procedures per surgeon. Dr. D'onofrio ranks #44 out of 370 orthopedic surgeons in Ohio.

What types of joint replacement does Dr. D'onofrio perform?

Dr. D'onofrio performs all three major joint replacement procedures: knee replacement (62 cases), hip replacement (37 cases), shoulder replacement (17 cases). This breadth indicates a comprehensive orthopedic joint replacement practice.

Where is Dr. D'onofrio's practice located?

Dr. D'onofrio practices in Lancaster, Ohio. The office is located at 2656 N Columbus St Ste D, Lancaster, OH 43130. Patients in the surrounding area can consult Dr. D'onofrio for joint replacement evaluation.

What does the Medicare data for Dr. D'onofrio represent?

The procedure counts shown are based on 2024 Medicare Part B fee-for-service claims data, published by the Centers for Medicare and Medicaid Services (CMS). Medicare fee-for-service is only one payer stream, and the share of national volume it represents differs by procedure. In 2024 the share was 23% to 28% for knee replacement, 25% to 33% for hip replacement, 29% to 37% for shoulder replacement, which puts Dr. D'onofrio's total volume across all insurers at roughly 380 to 480 procedures against the 116 verified here. Those shares are derived from published national volume projections rather than quoted from a single publication, and they are estimates with real uncertainty. The OrthoProcedures methodology page shows the full derivation, the sources, and the limits at orthoprocedures.com/data-methodology.html.

Has Dr. D'onofrio's procedure volume changed over time?

Dr. D'onofrio's procedure volume has been relatively stable over 12 years of Medicare data, ranging from 112 to 193 procedures per year between 2013 and 2024. Consistent volume over multiple years reflects a steady joint replacement practice.

Does Dr. D'onofrio perform more than one type of joint replacement?

Yes. Dr. D'onofrio's Medicare data shows procedures in knee replacement (62 cases), hip replacement (37 cases), shoulder replacement (17 cases). Performing all three major joint replacements places Dr. D'onofrio among the 5% of orthopedic surgeons nationally who cover hip, knee, and shoulder arthroplasty.

Which hospitals is Dr. D'onofrio affiliated with?

According to CMS facility affiliation data, Dr. D'onofrio is affiliated with Fairfield Medical Center, Hocking Valley Community Hospital, Genesis Hospital, Ohiohealth O'Bleness Hospital.

What are the quality ratings for hospitals where Dr. D'onofrio practices?

Fairfield Medical Center (2 out of 5 CMS stars, hip/knee complication rate similar to national average); Hocking Valley Community Hospital (insufficient case volume for complication rate comparison); Genesis Hospital (4 out of 5 CMS stars, insufficient case volume for complication rate comparison). These are hospital-level quality metrics from CMS Hospital Compare and do not reflect individual surgeon outcomes.

Patient Resources & Verification

Research reviews, verify credentials, and check official quality data through these trusted sources:

Medicare Care Compare and NPI Registry are official U.S. government sources. Google reviews reflect user-submitted feedback. OrthoProcedures.com does not verify the accuracy of third-party review content.

Cite This Data

APA: OrthoProcedures. (2026). Dr. Mark D'onofrio, M.D. -- Orthopedic Surgeon Profile. Retrieved from https://orthoprocedures.com/surgeons/oh/dr-mark-donofrio-lancaster.html

Link: https://orthoprocedures.com/surgeons/oh/dr-mark-donofrio-lancaster.html

Data source: CMS Medicare Part B Provider Utilization & Payment Data. Full methodology | Open Data API

Important: Rankings are based solely on Medicare procedure volume and do not reflect quality of care, patient outcomes, or procedures covered by private insurance. This data represents approximately one-third to 40% of all joint replacement procedures nationwide. Always consult with healthcare providers to make informed decisions about your care.